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Genetic & Molecular Testing in Lake Charles

Learn More about Your Breast Cancer Risks

Genetic and molecular tests have the potential to not only provide patients with personalized
diagnostic information, but also allow for specifically tailored treatment plans, thus limiting
resistance and toxicity. They also supply prognostic information about cancer in its early stages,
thereby determining whether aggressive, early management is necessary.

  • BRCA: There are several genes linked to an increased risk of breast cancer, but two of the most
    common are breast cancer genes 1 and 2 (BRCA1 and BRCA2). A mutation in either of these
    genes gives an increased risk of developing breast cancer and ovarian cancer. Blood tests
    (genetic tests) check for known mutations in these genes..
  • Mammoprint: This test uses information about 70 genes to predict the risk of the cancer coming back for early-stage, low-risk breast cancer.
  • Oncotype: This test evaluates 16 cancer-related genes and five reference genes to produce a number called the Recurrence Score. This score estimates the risk of recurrence (return of the cancer in a place other than the breast) within 10 years after diagnosis for women with stage I or stage II, node-negative, ER-positive breast cancer treated with hormonal therapy alone. It is mainly
    used to help make decisions about whether chemotherapy should be added to a person’s treatment.
  • ER/PR: Breast cancer cells depend on the hormones estrogen and/or progesterone to grow. The
    presence of these receptors helps determine both the risk of recurrence (cancer coming back
    after treatment) and the type of treatment most likely to prevent recurrence. Generally, hormonal
    therapy works well for ER-positive or PR-positive tumors, but chemotherapy is also used in
    specific situations. About 75% to 80% of breast cancers have estrogen and/or progesterone
    receptors.
  • Her2: About 20% to 25% of breast cancers have more copies of a gene called the human epidermal
    growth factor receptor 2 (HER2) than normal. Because this gene makes a protein that fuels
    tumor cell growth, HER2-positive cancers usually grow more quickly. The tumor’s HER2 status
    also helps determine whether a certain type of drug might help treat the cancer.

Click here for more information on our genetics program.

Talk to your primary care or oncologist to find out if breast cancer genetic testing is right for you.

Memorial Breast Health Oak Park Campus
(337) 494-4755

Memorial for Women Breast Health
(337) 480-7444